earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade. >>5 Stocks Ready to Break Out Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success. With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today. >>5 Big Stock Charts You Need to See Nektar Therapeutics Nektar Therapeutics ( NKTR) is a clinical-stage biopharmaceutical company developing a pipeline of drug candidates that utilize its PEGylation and polymer conjugate technology platforms, which are designed to improve the benefits of drugs for patients. This stock is trading up 3.4% to $9.34 in recent trading. Today's Range: $8.90-$9.37 52-Week Range: $5.65-$10.98 Volume: 518,000 Three-Month Average Volume: 944,082 Shares of NKTR are moving higher today ahead of its quarterly earnings report, which is due out on Feb. 28 after the market close. >>4 Biotech Stock Stars Losing Their Luster From a technical perspective, NKTR is spiking higher here right off some near-term support at $8.88 with decent upside volume. This stock has been trading inside of a consolidation pattern for the last month and change, with shares moving between $8.46 on the downside and $9.58 on the upside. Shares of NKTR are now quickly moving within range of triggering a breakout trade above the upper-end of its consolidation chart pattern. That breakout will hit if NKTR manages to take out some near-term overhead resistance levels at $9.41 to $9.58 with high volume.