Delcath SystemsAnother stock that's quickly moving within range of triggering a major breakout trade is Delcath Systems ( DCTH), which is a development-stage specialty pharmaceutical and medical device company focused on oncology, primarily cancers in the liver. This stock has been red hot in 2013, with shares up 28%. This company has a major catalyst on the horizon; it will hear from the FDA in June on the possible approval of Chemostat, which targets an inoperable liver cancer called mestastic melanoma. The estimated domestic market for metastic melanoma chemotherapy is $500 million. If you look at the chart for Delcath Systems, you'll see that this stock has been uptrending strong for the last three months, with shares skyrocketing higher from its low of $1.01 to its recent high of $1.68 a share. During that move, shares of DCTH have been mostly making higher lows and higher highs, which is bullish technical price action. That move has now pushed shares of DCTH within range of triggering a major breakout trade. Market players should now look for long-biased trades in DCTH once it manages to break out above some near-term overhead resistance levels at $1.68 to $1.70 a share with high volume. Look for a sustained move or close above those levels with volume that registers near or above its three-month average action of 1.4 million shares. If that breakout triggers soon, then DCTH will set up to re-test or possibly take its next major overhead resistance levels at $2.24 to $2.38 a share. Any high-volume move above those levels will then put $2.50 to $3 into range for shares of DCTH. Traders can look to buy DCTH off any weakness to anticipate that breakout and simply use a stop that sits right around its 50-day moving average of $1.40 a share. One can also buy DCTH off strength once it clears those breakout levels with volume and then simply use a stop right below some near-term support at $1.50 to $1.46 a share. The short interest for DTCH isn't massive at 8.8% of the float, but the bears have been adding to that position from the last reporting period by 11.9%, or about 701,000 shares. We could see the sellers cover some of those bets if DTCH breaks out soon, so make sure to have this on your trading radar.