Dynavax TechnologiesDynavax Technologies ( DVAX), a clinical-stage biopharmaceutical company, discovers and develops novel products to prevent and treat infectious diseases, asthma and inflammatory and autoimmune diseases. This stock closed up 3.6% to $3.15 on Tuesday. Tuesday's Range: $3.01-$3.21 52-Week Range: $2.22-$5.34 Volume: 6.07 million Three-Month Average Volume: 3.76 million From a technical perspective, DVAX spiked higher here right off its 50-day moving average of $2.92 with massive upside volume. This move is quickly pushing shares of DVAX within range of triggering a major breakout trade. That trade will hit if DVAX manages to take out some near-term overhead resistance at $3.39 with high volume. Traders should now look for long-biased trades in DVAX as long as it's trending above its 50-day at $2.92, and then once it sustains a move or close above $3.39 with volume that hits near or above 3.76 million shares. If that breakout triggers soon, then DVAX will set up to re-fill some of its gap down zone from last November that started around $4.75. Some possible upside targets if DVAX gets into that gap are its 200-day at $3.90 to $4.25. AthersysAthersys ( ATHX) is a biopharmaceutical company focused in the field of regenerative medicine. This stock closed up 3.8% to $1.34 on Tuesday. Tuesday's Range: $1.30-$1.37 52-Week Range: $0.95-$2.33 Volume: 1.19 million Three-Month Average Volume: 411,960 From a technical perspective, ATHX spiked higher here back above its 200-day moving average of $1.33 with monster upside volume. This stock has been uptrending strong for the last three months, with shares soaring from its low of 95 cents to its recent high of $1.37. During that move, shares of ATHX have been consistently making higher lows and higher highs, which is bullish technical price action. That move has now pushed ATHX within range of triggering a near-term breakout trade. That trade will hit if ATHX manages to take out some near-term overhead resistance levels at $1.37 to $1.47 and then once it clears more resistance at $1.60 with high volume.