Pernix Therapeutics To Ring The NASDAQ Stock Market Opening Bell

Pernix Therapeutics Holdings, Inc. (“Pernix” or the “Company”) (NASDAQ: PTX), a specialty pharmaceutical company, today announced that it is scheduled to ring The NASDAQ Stock Market Opening Bell at 9:30 am EST on Monday, January 28, 2013 to celebrate the Company's listing on the NASDAQ Global Market. The Company’s common stock will begin trading on the NASDAQ on January 28, 2013.

Access to the NASDAQ MarketSite webcam feed is available to view the ceremony live by launching this link, http://www.nasdaq.com/about/marketsitetowervideo.asx at 9:20 a.m. EST. To watch, under the heading MarketSite at the bottom of the page click on Windows Media Player.

Cooper Collins, President and CEO of Pernix, said, “We are pleased to ring the NASDAQ Opening Bell, celebrating our new listing and recent completion of the acquisition of Cypress Pharmaceuticals and Hawthorn Pharmaceuticals.”

About Pernix Therapeutics Holdings, Inc.

Pernix Therapeutics is a specialty pharmaceutical company primarily focused on the sales, marketing, manufacturing and development of branded, generic and OTC pharmaceutical products. The Company manages a portfolio of branded products, including the recently acquired Hawthorn Pharmaceuticals’ product line. The Company’s branded products for the pediatrics market include CEDAX®, an antibiotic for middle ear infections, NATROBA™, a topical treatment for head lice marketed under an exclusive co-promotion agreement with ParaPRO, LLC, and a family of treatments for cough and cold (ZUTRIPRO®, BROVEX®, ALDEX® and PEDIATEX®). The Company’s branded products for gastroenterology include OMECLAMOX-PAK®, a 10-day treatment for H. pylori infection and duodenal ulcer disease, and REZYST™, a probiotic blend to promote dietary management. The Company promotes its branded pediatric and gastroenterology products through its sales force. Pernix markets its generic products through its wholly-owned subsidiaries, Cypress Pharmaceuticals and Macoven Pharmaceuticals. The Company’s wholly-owned subsidiary, Great Southern Laboratories, manufactures and packages products for the pharmaceutical industry in a wide range of dosage-forms. A product candidate utilizing cough-related intellectual property is in development for the U.S. OTC market. Founded in 1996, the Company is based in The Woodlands, TX.

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