"The most popular Combo-Pilling duo seems to be Relacore®, called 'America's #1 Belly Fat Pill,' and Zantrex®-3, the high-energy diet pill that's been a consumer favorite for years," says Chantelle Daines, a Majestic Media analyst. "People are making claims of huge weight-loss success when they Combo-Pill with these two, possibly because Relacore helps address problematic nervous binge eating and stress-related belly fat, while Zantrex was formulated for rapid weight loss and an incredible burst of energy."Both Relacore and Zantrex are readily available at WalMart, Walgreens, CVS, Rite Aid, and smarter retailers nationwide. It's a bit more difficult to find them online because you have to go to two separate websites. You can find Zantrex at www.Zantrex3.com and Relacore at www.Relacore.com. For some, using a supplement that offers dual weight-loss products in one easy package is more appealing. The most powerful in this category is called BiphedAdrene®, the Super Powerful "Diet Pill" that's been flying off store shelves. Biphed's maker revealed to Ms. Daines that BiphedAdrene is a two-part system comprised of a unique "Complex Phenylethylamine Provisional" (for powerful appetite control, mood-elevation, and energy) — the "Purple Pill" — combined with an aggressive thermogenic compound (for fat burning and stamina) — the "Yellow Pill." This two-pronged attack on fat is apparently what makes this "Combo-Pilling" superstar so effective... and so popular. BiphedAdrene is available exclusively at GNC or direct from the manufacturer at www.Biphed.com. A 30-day supply costs $135, but if you use promo code COMBO at the manufacturer's website you get $25 off and free shipping. † And it's not just the dietary supplement industry that's returning to Combo-Pilling. The U.S. FDA has just approved Qsymia (formerly Qnexa). It's a combo of phentermine, an appetite suppressant that was half of the Fen-Phen diet pill, and topiramate, which was originally designed as a drug to treat epilepsy and seizures. Because it's a drug, not a dietary supplement, you need to visit your doctor and get a prescription if you're interested in trying this Combo-Pill.