The "Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures" guideline replaces the previous AAOS Information Statement, "Antibiotic Prophylaxis for Bacteremia in Patients with Joint Replacement." The full guideline along with all supporting documentation and workgroup disclosures is available on the AAOS website: http://www.aaos.org/guidelines and the ADA website: http://www.ada.org/2583.aspx?currentTab=2#replace .1) HCUPnet. Healthcare Cost and Utilization Project (HCUP). 1993-2010. Agency for Healthcare Research and Quality, Rockville, MD. http://hcupnet.ahrq.gov/ Accessed November 29, 2012. 2) Della Valle CJ, Zuckerman JD, Di Cesare PE. Periprosthetic Sepsis. Clin Orthop 2004;(420):26-31. 3) American Academy of Orthopaedic Surgeons and the American Dental Association Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures Guideline. Rosemont (IL): AAOS: 2012. More about AAOS Evidence-based Clinical Practice GuidelinesThis guideline is an educational tool to guide clinicians through treatment decisions in an effort to improve the quality and effectiveness of care. This guideline should not be construed as including all methods of care or excluding methods of care reasonably directed to obtaining the same results. The decision regarding any specific procedure or treatment must be made in light of all circumstances presented by the patient, the needs and resources particular to the locality or institution, and the clinical judgment of the provider. About the American Academy of Orthopaedic SurgeonsThe American Academy of Orthopaedic Surgeons (AAOS) is the premier not-for-profit organization that helps excel the orthopaedic practice through educational programming for orthopaedic surgeons and allied health professionals. The Academy champions the interests of patients and advances the highest quality of bone and joint health. Founded in 1933, AAOS has more than 37,000 orthopaedic surgeon members that specialize in the treatment, both surgical and nonsurgical, of injuries to the musculoskeletal system, including bones, joints, ligaments, tendons, muscles and nerves. The members of the Academy aim to increase people's quality of life by improving mobility, reducing pain, and returning patients to their jobs and hobbies. For more information on bone and joint health, visit orthoinfo.org.