>>5 Toxic Stocks to Dump Before 2013 Stocks that are making large moves like these are favorites among short-term traders because they can jump into these names and try to capture some of that massive volatility. Stocks that are making big-percentage moves either up or down are usually in play because their sector is becoming attractive or they have a major fundamental catalyst such as a recent earnings release. Sometimes stocks making big moves have been hit with an analyst upgrade or an analyst downgrade. Regardless of the reason behind it, when a stock makes a large-percentage move, it is often just the start of a new major trend -- a trend that can lead to huge profits. If you time your trade correctly, combining technical indicators with fundamental trends, discipline and sound money management, you will be well on your way to investment success. >>5 Dividend Stocks Itching to Pay You More With that in mind, let's take a closer look at a several stocks under $10 that are making large moves to the upside today.Amicus Therapeutics ( FOLD) This is a clinical-stage biopharmaceutical company is focused on the discovery, development and commercialization of a new class of orally-administered, small molecule drugs, for the treatment of a range of human genetic diseases. This stock is trading up 10.5% to $5.43 in recent trading. Today's Range: $4.93-$5.45 52-Week Range: $2.33-$7.29 Volume: 793,000 Three-Month Average Volume: 421,787 From a technical perspective, FOLD is ripping higher here back above both its 50-day at $5.25 and its 200-day at $5.28 with heavy upside volume. This move is quickly pushing FOLD within range of triggering a near-term breakout trade. That trade will hit once FOLD manages to take out some near-term overhead resistance at $5.60 with high volume. Traders should now look for long-biased trades in FOLD as long as it's trending above its 50-day at $5.25, and then once it sustains a move or close above $5.60 with volume that hits near or above 421,787 shares. If that breakout triggers soon, then FOLD will set up to re-test or possibly take out its next major overhead resistance levels at $6.82 to $6.89. Any high-volume move above those levels will then put $7.29 to $8 into focus for shares of FOLD.