1 Weinberg RA (2007) Cytoplasmic signaling circuitry programs many of the traits of cancer. In Jeffcock E, Zayatz E, and Mickey RK (Eds.) The biology of cancer (pp. 179-183). New York, NY: Garland Science, Taylor & Francis Group.2 Rommel C (2011) Taking PI3Kδ and PI3Kγ one step ahead: dual active PI3Kδ/γ inhibitors for the treatment of immune-mediated inflammatory diseases. In Rommel C, Vanhaesebroeck B, and Vogt PK, (Eds.) Phosphoinositide 3-kinase in Health and Disease (pp. 279-299). Springer Berlin Heidelberg.