Safeguard Scientifics, Inc. (NYSE: SFE), a holding company that builds value in growth-stage life sciences and technology companies, today announced that it will release its financial results for the third quarter ended September 30, 2012 prior to market open on Thursday, October 25, 2012. SAFEGUARD SCIENTIFICS THIRD QUARTER 2012 CONFERENCE CALL Please call at least 15 minutes prior to the call to register. Date: Thursday, October 25, 2012 Time: 9:00am EDT Webcast: www.safeguard.com/results Call-in Number: 877-317-6789(International) +412-317-6789 Replay Number: 877-344-7529(International) +412-317-0088 Replay Access Code: 1001974 Replay available through November 26, 2012 at 9:00am EST Speakers: President and CEO Peter J. Boni; Senior Vice President and CFO Stephen T. Zarrilli Format: Discussion of third quarter 2012 financial results followed by Q&A. For more information please contact IR@safeguard.com. About Safeguard Scientifics Founded in 1953 and based in Wayne, PA, Safeguard Scientifics, Inc. (NYSE: SFE) provides growth capital for entrepreneurial and innovative life sciences and technology companies. Safeguard targets life sciences companies in Molecular and Point-of-Care Diagnostics, Medical Devices, Regenerative Medicine, Specialty Pharmaceuticals and selected healthcare services, and technology companies in Internet / New Media, Financial Services IT, Healthcare IT and selected business services with capital requirements of up to $25 million. Safeguard participates in expansion financings, corporate spin-outs, management buyouts, recapitalizations, industry consolidations and early-stage financings. For more information, please visit our website at www.safeguard.com, our blog at blog.safeguard.com, download our web app at app.safeguard.com, or you can follow us on Twitter ( twitter.safeguard.com), StockTwits ( stocktwits.safeguard.com), SlideShare ( slideshare.safeguard.com), LinkedIn ( linkedin.safeguard.com), and YouTube ( youtube.safeguard.com).