One more stock that's been seeing with some decent insider buying is Bruker ( BRKR), a global manufacturer of scientific instruments that address the needs of an array of customers in life science, pharmaceutical, biotechnology, clinical and molecular diagnostics research, as well as in materials and chemical analysis in various industries and government applications. Insiders are buying this stock into some modest strength, since shares are up 8% so far in 2012. Bruker has a market cap of $2.25 billion and an enterprise value of $2.31 billion. This stock trades at reasonable valuation, with a trailing price-to-earnings of 27.06 and a forward price-to-earnings of 16.11. Its estimated growth rate for this year is -18.3%, and for next year it's pegged at 25.4%. This is not a cash-rich company, since the total cash position on its balance sheet is $240.30 million and its total debt is $321.40 million. A director and beneficial owner just bought 100,000 shares, or $1.3 million worth of stock, at $13 per share. The CEO also just bought 100,000 shares, or $1.3 million worth of stock, at $13 per share. From a technical perspective, BRKR is currently trading above its 50-day moving average and below its 200-day moving average, which is neutral trendwise. This stock gapped down big in July from around $14 to a low of $9.91 a share with massive volume. Since that gap down, shares of BRKR have been uptrending towards its current price of $13.50 a share. During that uptrend, shares of BRKR have mostly made higher lows and higher highs, which is bullish technical price action. That move has now pushed BRKR within range of triggering a near-term breakout trade. If you're bullish on BRKR, then I would look for long-biased trades once it manages to break out above some near-term overhead resistance levels at $13.96 to $14.29 a share with high volume. Look for a sustained move or close above those levels with volume that tracks in close to or above its three-month average action of 778,623 shares. If that breakout triggers soon, then BRKR will have a great chance of re-testing or possibly taking out its next significant overhead resistance level at $15.75 a share. On the flip side, I would avoid BRKR or look for short-biased trades if it fails to trigger that breakout, and then drops back below its 50-day at $12.50 with heavy volume. If we get that move, then BRKR will setup to re-test or possibly take out its next major support levels at $11.50 to $11 a share. To see more stocks with notable insider buying, check out the Stocks With Big Insider Buying portfolio on Stockpickr. -- Written by Roberto Pedone in Winderemere, Fla.