BALTIMORE ( Stockpickr) -- Do you own any toxic stocks in your portfolio?If you do, it makes sense to sell before they get out of hand. Now more than ever, the toxic stocks are sending an important message to Wall Street. With the S&P 500 up more than 16% year-to-date, the few stocks that aren't participating in this rally are the ones that you really want to unload. To be fair, the companies I'm talking about today aren't exactly "junk." >>5 Stocks Poised for Breakouts I mean, they're not next up in line at bankruptcy court. But that's frankly irrelevant; from a technical analysis standpoint, they're some of the worst positioned names out there right now. For that reason, fundamental investors need to decide how long they're willing to take the pain if they want to hold onto these firms this Fall. And for investors looking to buy one of these positions, it makes sense to wait for more favorable technical conditions (and a lower share price) before piling in. For the unfamiliar, technical analysis is a way for investors to quantify qualitative factors, such as investor psychology, based on a stock's price action and trends. Once the domain of cloistered trading teams on Wall Street, technicals can help top traders make consistently profitable trades and can aid fundamental investors in better planning their stock execution. >>5 Big Stocks Ready to Slingshot Higher So, without further ado, let's take a look at five "poison stocks" you should be unloading in September.