BEDMINSTER, N.J., and DUBLIN, Ireland, Sept. 5, 2012 (GLOBE NEWSWIRE) -- Amarin Corporation plc (Nasdaq:AMRN), a biopharmaceutical company focused on the commercialization and development of therapeutics to improve cardiovascular health, announced today that the United States Patent and Trademark Office (USPTO) has published notification of Notices of Allowance for two additional U.S. Patent Applications, Serial Numbers 12/702,889 and 13/349,153. These applications include claims intended to protect the Vascepa™ (icosapent ethyl) indication approved in July 2012 by the U.S. Food and Drug Administration (FDA) based on Amarin's MARINE clinical trial results. A Notice of Allowance is issued after the USPTO makes a determination that a patent can be granted from an application. The issued patents would have terms that expire no earlier than in 2030. After issuance, Amarin plans to list both patents in the FDA's Approved Drug Products with Therapeutic Equivalence Evaluations, or Orange Book. "These Notices of Allowance are based upon showings that the clinical results for Vascepa in Amarin's MARINE trial were surprising and unexpected, key factors considered by the USPTO in granting a patent," stated Joseph Zakrzewski, Chairman and CEO of Amarin. "Amarin's goal is to protect the commercial potential of Vascepa to beyond 2030 through patent protection, regulatory exclusivity and trade secrets and by taking advantage of manufacturing barriers to entry. The issuance of these Notices of Allowance represents additional significant steps toward achieving this goal." These Notices of Allowance follow the issuance of U.S. Patent Number 8,188,146, a Notice of Allowance for U.S. Patent Application Serial Number 12/769,885 and the September 4, 2012 announcement of a Notice of Allowance for U.S. Patent Application Serial Number 13/282,145. These applications are part of an expanding patent portfolio for Amarin with seven patent applications now either issued, allowed or in advanced stages of prosecution with the USPTO and over 25 additional applications pending in the United States. Amarin is also pursuing patent applications related to Vascepa in multiple jurisdictions outside the United States, including the application for Amarin's MARINE method of use patent in Europe for which Amarin has announced receipt of an Intention to Grant letter.