About the Bristol-Myers Squibb and AstraZeneca CollaborationBristol-Myers Squibb and AstraZeneca entered into a collaboration in January 2007 to enable the companies to research, develop and commercialize certain investigational drugs for type 2 diabetes. The Bristol-Myers Squibb/AstraZeneca diabetes collaboration is focused around ONGLYZA ® (saxagliptin), part of the innovative class of DPP-4 inhibitors, KOMBIGLYZE ® (saxagliptin and metformin HCI extended-release) and FORXIGA ® (dapagliflozin), an investigational SGLT2 inhibitor, and is dedicated to global patient care, improving patient outcomes and creating a new vision for the treatment of diabetes. ONGLYZA has been submitted for regulatory approval in 93 countries and is approved in 77 countries including the US, Canada, Mexico, EU, India, Brazil and China. FORXIGA received a positive opinion from the CHMP in Europe in April 2012. The expansion of the collaboration covers the co-development and marketing of products in the Amylin Pharmaceuticals portfolio, which include BYETTA ® (exenatide) and BYDUREON ® (exenatide extended-release for injectable suspension/exenatide 2 mg powder and solvent for prolonged release suspension for injection) for the treatment of type 2 diabetes, metreleptin, an investigational leptin analogue currently under review by the U.S. Food and Drug Administration (FDA) for the treatment of lipodystrophy, and SYMLIN ® (pramlintide acetate), an amylin analogue, approved by the FDA for the treatment of type 1 and type 2 diabetes patients with inadequate glycaemic control on meal-time insulin. About AstraZeneca AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialization of prescription medicines for gastrointestinal, cardiovascular, neuroscience, respiratory and inflammation, oncology and infectious disease. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit: www.astrazeneca.com. About Bristol-Myers Squibb Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. For more information, please visit http://www.bms.com or follow us on Twitter at http://twitter.com/bmsnews. About Amylin Pharmaceuticals Amylin Pharmaceuticals is a biopharmaceutical company dedicated to improving lives of patients through the discovery, development and commercialization of innovative medicines. Amylin is committed to delivering novel therapies that transform the way diabetes and other metabolic disorders are treated. The acquisition of Amylin by Bristol-Myers Squibb was completed August 9, 2012. More information about Amylin Pharmaceuticals is available at www.amylin.com.