In the absence of positive, definitive actions that will maximize shareholder value, I intend to pursue alternatives. If the Board is truly focused on maximizing shareholder value, the shareholders need to see that you are attuned to achieving positive results now, rather than later. The status quo has not produced shareholder value for a decade, and is no longer acceptable to me, and it should not be acceptable to the Board.I appreciate your time and I hope to have a constructive dialogue with the Board regarding Repligen's business, assets, strategy and operations. Patience is no longer a virtue. Best regards, /s/ Ronald L. Chez Ronald L. Chez (312) 944-0987 SOURCE Ronald L. Chez, Inc.