GREENWOOD VILLAGE, Colo., July 13, 2012 /PRNewswire/ -- Ampio Pharmaceuticals, Inc. (Nasdaq: AMPE), a biopharmaceutical company conducting clinical trials on its three lead drugs (Ampion™, Optina™ & Zertane™), licensing distribution of these drugs and developing additional new drugs, today announced the exercise in full of the over-allotment option granted to the underwriters by Ampio and certain of its stockholders with respect to the purchase of 692,310 shares of common stock at a public offering price of $3.25 per share. The over-allotment option is being exercised in connection with Ampio's previously announced underwritten public offering of 4,615,400 shares of common stock, which was subsequently increased by 181,250 shares to an aggregate of 4,796,650 such shares. As a result of the exercise of the over-allotment option and the additional 181,250 shares of common stock purchased in the previously announced public offering, the total gross proceeds to Ampio from the offering will be approximately $16,912,545, before deducting the underwriting discount and other estimated offering expenses. (Logo: http://photos.prnewswire.com/prnh/20120516/MM09116LOGO) Aegis Capital Corp. and Fordham Financial Management, Inc. are acting as joint book-running managers for the offering. The offering is being made pursuant to a shelf registration statement that Ampio filed with the Securities and Exchange Commission ("SEC") and is effective. A preliminary prospectus supplement and accompanying base prospectus relating to the offering were filed with the SEC and a final prospectus supplement and accompanying base prospectus will be filed with the SEC. When available, copies of the final prospectus supplement and accompanying base prospectus relating to the offering may be obtained by contacting Aegis Capital Corp., Prospectus Department, 810 Seventh Avenue, 18th Floor, New York, NY, 10019, telephone: 212-813-1010 or email: email@example.com or Fordham Financial Management, Inc., 17 Battery Place, South, Suite 643, New York, New York 10004. Electronic copies of the final prospectus supplement and accompanying base prospectus will also be available on the website of the SEC at http://www.sec.gov. This press release does not constitute an offer to sell, or the solicitation of an offer to buy, these securities, nor will there be any sale of these securities in any state or other jurisdiction in which such offer, solicitation or sale is not permitted.