Another name to look at with some interesting insider buying is biotechnology and drugs player United Therapeutics ( UTHR), which is focused on the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening conditions. This stock hasn't done much at all so far in 2012 with shares up just under 2%. United Therapeutics has a market cap of $2.58 billion and an enterprise value of $2.41 billion. This stock trades at a cheap valuation, with a trailing price-to-earnings of 10.14 and a forward price-to-earnings of 9.60. Its estimated growth rate for this year is 27%, and for next year it's pegged at 7.7%. This is a cash-rich company, since the total cash position on its balance sheet is $408.97 million and its total debt is $268.16 million. After you back out the debt, United Therapeutics has a total of $140.81 million of cash on its books. >>Hot Biopharma Stocks With Breakout Potential in 2012 The CEO just bought 3,960 shares, or about $189,000 worth of stock, at $47.95 per share. The same CEO also just bought 4,138 shares, or about $198,000 worth of stock, at $47.94 per share. From a technical perspective, UTHR is currently trading above both its 50-day and 200-day moving averages, which is bullish. Since this stock hit a low of $40.34 in April, shares have started to uptrend strong and make higher highs and higher lows, which is bullish technical price action. That move is quickly pushing UTHR within range of triggering a major breakout trade. If you're bullish on UTHR, then I would look for long-biased trades once this stock triggers a break out above some past overhead resistance at $49.13 to $49.17 a share with high-volume. Look for volume on that move that hits near or above its three-month average action of 724,127 shares. If we get that move soon, then UTHR will have a great chance of re-testing and possibly taking out its next significant overhead resistance levels at $51.12 to $51.98 a share. I would simply avoid UTHR or look for short-biased trades if it fails to trigger that breakout, and then drops back below some near-term support at $47 to $46 a share with high-volume. If we get that action soon, then UTHR could re-test and possibly take out its 200-day moving average of $44.29, and its 50-day moving average of $43.82 a share. United Therapeutics shows up on a list of Hot Biotech Stocks Traded by Hedge Funds. To see more stocks with notable insider buying like Sonus Networks ( SONS), CytRx ( CYTR) and ZBB Energy ( ZBB), check out the Stocks With Big Insider Buying portfolio on Stockpickr. -- Written by Roberto Pedone in Winderemere, Fla.