Expected five-year price gain:13.9% This metro area of some 200,000 people just north of the California border in south-central Oregon has had high unemployment in recent years, but Colpitts sees an improvement coming. "Medford has grown a lot over the past decade and has more employers these days," he says. "More jobs translate to more home purchasers." Historically a farming area, Medford has become a regional hub for medical care, as well as a destination for more and more retirees. The city also hosts the New York Stock Exchange-listed Lithia Motors ( LAD) chain of car dealerships, the famous Harry & David food company (parent of the Fruit-of-the-Month Club) and a few other important employers. As for housing, Realtor.com lists some 350 Medford properties for sale, priced from $33,000 for a two-bedroom condo to $2.3 million for a four-bedroom home on 166 acres.