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NEW YORK ( TheStreet) -- Shares of Onyx Pharmaceuticals (Nasdaq: ONXX) have taken a tremendous swing upward. The stock is trading at $61.63 as of 9:30 a.m. ET, 38.3% above Wednesday's closing price of $44.58. Volume is at 4.8 million, 3.4 times the daily average of 1.4 million.