NEW YORK ( TheStreet) -- Shares of Alexza Pharmaceuticals (Nasdaq: ALXA) were gapping down Wednesday morning with an open price 13.8% lower than Tuesday's closing price. The stock closed at $3.63 Tuesday and opened today's trading at $3.13. The average volume for Alexza has been 1.6 million shares per day over the past 30 days. Alexza has a market cap of $40.9 million and is part of the health care sector and drugs industry. Shares are down 56% year to date as of the close of trading on Tuesday. Alexza Pharmaceuticals, Inc., a pharmaceutical company, engages in the research, development, and commercialization of novel proprietary products for the acute treatment of central nervous system conditions worldwide. TheStreet Ratings rates Alexza as a sell. The company's weaknesses can be seen in multiple areas, such as its disappointing return on equity, generally disappointing historical performance in the stock itself and generally weak debt management. You can view the full Alexza Ratings Report. Get more investment ideas from our investment research center.