NEW YORK ( TheStreet) -- Santarus (Nasdaq: SNTS) is trading at unusually high volume Wednesday with two million shares changing hands. It is currently at 4.6 times its average daily volume and trading down 36 cents (-5.3%) at $6.44 as of 4 p.m. ET. Santarus has a market cap of $375.1 million and is part of the health care sector and drugs industry. Shares are up 105.4% year to date as of the close of trading on Tuesday. Santarus, Inc., a specialty biopharmaceutical company, engages in acquiring, developing, and commercializing proprietary products that address the needs of patients treated by physician specialists. The company has a P/E ratio of 66.6, equal to the average drugs industry P/E ratio and above the S&P 500 P/E ratio of 17.7. TheStreet Ratings rates Santarus as a hold. The company's strengths can be seen in multiple areas, such as its robust revenue growth, largely solid financial position with reasonable debt levels by most measures and impressive record of earnings per share growth. However, as a counter to these strengths, we find that the company's return on equity has been disappointing. You can view the full Santarus Ratings Report. See all heavy volume stocks in our stocks moving on unusual volume list or get investment ideas from our investment research center.