Celldex Therapeutics ( CLDX) is a biopharmaceutical company, which applies its Precision Targeted Immunotherapy Platform to generate a pipeline of candidates to treat cancer and other difficult-to-treat diseases. This stock is trading up 3.1% at $4.54 in recent trading. Today's Range: $4.47-$4.62 52-Week Range: $2.05-$5.66 Volume: 858,000 Three-Month Average Volume: 1.1 million Shares of CLDX are trading sharply higher in front of the company's upcoming catalyst. On May 23, CLDX will release data on its Phase IIb clinical trial for CDX-011, the company's investigative treatment for breast cancer. From a technical perspective, CLDX has started to move back above its 50-day moving average today of $4.44 on decent volume. This move is quickly pushing CLDX within range of triggering a near-term breakout trade. That trade will hit once CLDX takes out some near-term overhead resistance at $4.78 with high-volume. Traders should now look for long-biased trades once CLDX sustains a move or close above $4.78 with volume that's near or well above 1,124,690 shares. If we get that action soon, look for CLDX to tag its next significant overhead resistance levels at $5.47 to $5.66 in the near future.