NEW YORK (TheStreet) -- Jana Partners, a hedge fund with an activist investing bent, is betting on Marathon Petroleum ( MPC) to be a big payday in 2012. Jana has been on the right end of several big investments, including the Monday announcement that Barnes & Noble ( BKS) is spinning off its Nook business in a major deal with Microsoft. Jana's bet on Marathon Petroleum specifically is interesting in light of another major Monday deal in the energy space, with the sale of Sunoco to Energy Transfer Partners for $5.3 billion. David DiDomenico, a partner at Jana, said that the fund has targeted Marathon Petroleum because of the value in the company's logistics and midstream operations, which are hidden in its larger refining business. Before the ETP acquisition, Sunoco was in the process of exiting the refinery business to to focus on energy logistics and infrastructure. Get Ready for the M&A Boom >> "In Marathon, what we saw was the perfect mix of assets that we wanted to invest in." DiDomenico said that the company's midstream business will profit from a U.S. energy boom based of shale discoveries, representing 35% of the company's earnings, roughly triple current estimates. DiDomenico made his comments at the IMN Active-Passive Investor Summit in midtown New York on Monday. DiDomenico said the fund made its investment in November on the heels of Enbridge Energy's decision to reverse the flow of the Seaway Pipeline in the U.S. after buying it from ConocoPhillips. The dip in the spread between WTI crude and Brent crude as a result of the pipeline reversal and a drop in refiners gave Jana Partners a value entrance into Marathon Petroleum's stock in the low $30s, said DiDomenico. The stock was trading above $41 on Monday, though flat on the heels of the Sunoco news. DiDomenico said the Sunoco deal targets the oil and gas logistics business and the expected growth of the industry as new drilling methods lead to an increase in U.S. energy production. Last year's spinoffs and sale of El Paso -- Kinder Morgan bought the company in the largest M&A deal of the year -- also targeted the transport of energy. El Paso was a Jana investment. 10 Stocks Poised to Rise in Apple's Wake >> Nevertheless, it was a recent non-activist investment that is giving Jana what could be its best recent investment.