Danaher The industrial products manufacturer reported first-quarter earnings of $612.9 million, or 73 cents a share, up from year-earlier earnings of $429.4 million, or 61 cents. "The quarter progressed largely as we expected and we were particularly pleased with our team's execution which led to excellent core operating margin expansion, cash flow and earnings performance," CEO Lawrence Culp said in a statement. "In addition, we were encouraged by the sequential business improvement within the quarter and anticipate core growth will accelerate in the second quarter. With improving core growth, the cost reductions undertaken in 2011 and an attractive acquisition environment, we believe we are well positioned for the balance of 2012 and beyond." Danaher narrowed its guidance for full-year 2012 net earnings to between $3.25 and $3.35 a share. Previous guidance was for between $3.20 and $3.35. Shares of Danaher fell 47 cents, or 0.86%, in premarket trading Thursday to $54.22. TheStreet Ratings gives Danaher an A+ grade with a buy rating and $62.94 price target.