NEW YORK ( TheStreet) -- Orexigen Therapeutics (Nasdaq: OREX) is trading at unusually high volume Friday with 2.2 million shares changing hands. It is currently at 4.2 times its average daily volume and trading down 47 cents (-10.4%) at $4.07 as of 11 a.m. ET. Orexigen has a market cap of $114.4 million and is part of the health care sector and drugs industry. Shares are up 182% year to date as of the close of trading on Thursday. Orexigen Therapeutics, Inc., a development stage company, focuses on the development of pharmaceutical product candidates for the treatment of obesity. TheStreet Ratings rates Orexigen as a sell. The area that we feel has been the company's primary weakness has been its feeble growth in its earnings per share. You can view the full Orexigen Ratings Report. See all heavy volume stocks in our stocks moving on unusual volume list or get investment ideas from our investment research center. Interested in other stocks that are falling on unusually high volume? Get free SMS text alerts sent to you when the action happens by texting HVDOWN to 95370 or select from multiple alert options.