Mannatech, Incorporated (NASDAQ: MTEX), the leading innovator and provider of nutritional supplements based on Real Food Technology® solutions, recently announced the publication of a comprehensive literature review reporting the effects of polysaccharides on brain function. Dr. Erika Nelson, a neuroscientist, and her colleagues reviewed controlled studies assessing various roles of exogenous saccharide compounds and polysaccharide-rich extracts on brain function, with a significant focus on benefits derived from oral intake. Her review includes a discussion of five randomized, double-blind, placebo-controlled clinical trials that indicate that Ambrotose ® complex, a Mannatech product, positively impacts well-being, memory, cognitive function and mood in healthy adults.* Numerous preclinical studies were also identified that indicate various polysaccharides can modify behavior, enhance synaptic plasticity and provide neuroprotective effects. “Mannatech has consistently demonstrated a strong commitment to evaluating the impact of oral polysaccharide compounds on human health,” said Dr. Robert Sinnott, CEO and Chief Science Officer at Mannatech. “In 2010, we published a review—which has been of great interest to the scientific community—which consolidated the extant literature reporting significant impacts of oral polysaccharides on immune function. Today, we are once again pleased to offer an important consolidation of the literature investigating the impact of oral polysaccharides on brain health and function. This literature review both clarifies the current state of the science in this area and suggests appropriate avenues for future research that will help us better understand the benefits of these important compounds.” Dr. Nelson earned her BS in Genetics from the University of Kansas in Lawrence and went on to obtain her PhD in Neuroscience at the University of Texas Southwestern Medical Center in Dallas. She has published a number of papers on neurodevelopmental disorders and brain epigenetics. A candidate for a Masters of Business Administration at the University of Texas at Dallas, Dr. Nelson is also a consultant for Mannatech. Co-authors of the review include Dr. Robert Sinnott; Dr. Talitha Best, a scientist with dual appointments at the University of South Australia, Adelaide, and Swinburne University of Technology, Victoria, Australia; and Jane Ramberg, Director of Product Substantiation at Mannatech.