- IMO-2055, a TLR9 agonist – Idera recently announced positive from a Phase 1b results of IMO-2055 in combination with Tarceva® and Avastin® in patients with advanced non-small cell lung cancer. Results from a Phase 2 study of IMO-2055 in combination with Erbitux® for the treatment of squamous cell cancer of the head and neck are expected in the second quarter of 2012
- TLR 7,8 and 9 agonists – Idera recently announced that Merck has selected several novel TLR agonists targeted to TLR7, TLR8 or TLR9 for evaluation and use as vaccine adjuvant candidates under the companies' collaboration and license agreement
- IMO-4200 – Idera-4200 is a dual agonist of TLR7 and 8. Idera has conducted preclinical studies of IMO-4200 for hematological malignancies
- TLR3 agonists – Idera has identified novel TLR3 agonists for potential use as adjuvants in combination with cancer vaccines
IMO(R) and Idera(R) are our trademarks. All other trademarks and service marks appearing in this release are the property of their respective owners.