Shares of San Antonio, Texas- based Cullen Frost ( CFR) have gained nearly 7% year to date and is off by 5% over a one-year period. Cullen/Frost had total assets worth $20.317 billion as of Dec. 31. The bank reported a fourth-quarter net income of $55.4 million or 90 cents per share compared to $53.1 million or 87 cents per share in the fourth quarter of 2010. Fourth quarter return on average assets was 1.12%. While the bank ranks high on profitability metrics and has been a consistent performer among the regionals, the stock trades at nearly two times its tangible book, making it among the more expensive bank stocks. "We believe the company will continue to perform well fundamentally, with a credit and growth profile that is superior to peers. That said, given the higher relative valuation, we believe Cullen/Frost will have a difficult time outperforming the peer group," RBC Capital analysts wrote in a report. Out of 19 analysts covering the stock, only one analyst has a buy rating on the stock. 14 have a neutral rating while four analysts have a sell or underperform rating on the stock. The stock has a consensus price target if $54.42, which is below Tuesday's closing price of $56.26.