WINDERMERE, Fla. ( Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are hitting new 52-week highs and 52-week lows.

When you see a stock that's hitting new 52-week highs, it often means that the uptrend is very strong and the buyers are in full control (and the opposite for stocks setting new 52-week lows). Momentum traders often look at the 52-week high lists to find new trading ideas. Keep in mind, though, that new highs can also mean that the stock is overbought or has run up too far too fast.

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That's why it's important to combine a number of technical indicators such as volume, price, trend and momentum indicators such as RSI before you make an investing or trading decision. Combine all of those things with fundamental trends, disciple and sound money management and you will be well on your way to investment success.

With that in mind, let's take a closer look at several stocks that hit new 52-week highs today.

SonoSite

SonoSite ( SONO) specializes in the development of hand-carried ultrasound systems for use in a variety of medical specialties in a range of clinical settings. This stock is trading down 0.21% to $42.37 in recent trading after it hit a 52-week high of $43.00 earlier today.

Today's Range: $42.34-$43.00

52-week Range: $25.74-$43.00

Volume: 24,000

Three-Month Average Volume: 212,383

SonoSite has a market cap of $595.57 million and an enterprise value of $622.02 million. This stock trades at a trailing price-to-earnings of 95.81 and a forward price-to-earnings of 28.30. Its estimated revenue growth for this year is 12.1%, and for next year it's pegged at 104.1%.

From a technical standpoint, this stock is approaching a big breakout today with shares flirting with some past overhead resistance at $42.70. Market players should now watch for a sustained move and close on high-volume above $42.70 to signal that this stock wants to trend much higher. So far today the volume isn't there, so watch how the stock closes.

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Nathan's Famous

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Nathan's Famous ( NATH) operates in the foodservice industry, marketing the Nathan's Famous brand and selling products bearing the Nathan's Famous trademarks through various channels of distribution in the U.S. and internationally. This stock is trading up 9.8% to $20.95 in recent trading after hitting a 52-week high of $21.25 earlier in the day.

Today's Range: $20.75-$21.25

52-week Range: $15.75-$21.25

Volume: 37,000 shares

Three-Month Average Volume: 5,017 shares

Nathan's Famous has a market cap of $104.28 million and an enterprise value of $62.70 million. This stock trades at a trailing price-to-earnings of 25.83.

From a technical standpoint, this stock is gapping up big today above some past overhead resistance at $19.50 a share. The problem here is that the stock is very thinly traded with only 5,017 shares trading on an average day. That lack of interest from the big fish on Wall Street would have me avoiding this for any short-term trading.

MercadoLibre

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MercadoLibre ( MELI) hosts an online commerce platform in Latin America located at www.mercadolibre.com which is focused on enabling e-commerce and its related services. This stock is trading up 3% at $93.93 in recent trading after hitting a 52-week high of $95.48 earlier in the day.

Today's Range: $91.00-$95.48

52-week Range: $48.30-$95.48

Volume: 633,000 shares

Three-Month Average Volume: 656,925 shares

MercadoLibre, one of TheStreet Ratings' top-rated Internet stocks, has a market cap of $4.11 billion and an enterprise value of $3.89 billion. The stock trades at a trailing price-to-earnings of 57.84 and a forward price-to-earnings of 39.94. Its estimated growth rate for this year is 37.8%, and for next year it's pegged at 33.1%.

From a technical standpoint, this stock broke out earlier in the trading session above $89.99, but has since then reversed course off the daily highs and is now showing some bearish signs. Market players should watch for a bearish short trade to trigger if MELI closes below $89.99 on high-volume. Volume at last check is already tracking in very high, so watch the closing price.

Fastenal

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Fastenal ( FAST) sells industrial and construction supplies in a wholesale and retail fashion. This stock is trading up 1% at $42.92 in recent trading after hitting a 52-week high of $43.04 earlier in the day.

Today's Range: $$42.45-$43.04

52-week Range: $$28.81-$43.04

Volume: 1.1 million shares

Three-Month Average Volume: 2.75 million shares

Fastenal, one of TheStreet Ratings' top-rated supplier and distributor stocks, has a market cap of $12.69 billion and an enterprise value of $12.42 billion. The stock trades at a trailing price-to-earnings of 38.02 and a forward price-to-earnings of 30.47. Its estimated growth rate for this year is 35.6%, and for next year it's pegged at 15.6%.

From a technical standpoint, this stock has started to flirt with a big breakout level now that shares are bumping up against some past overhead resistance at $41.65. Market players should now watch for a sustained move and close on high-volume above $41.65 to trigger a breakout trade. Look for volume that's tracking in close to or above 2,752,740 shares on a close above $41.65.

Genomic Health

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Genomic Health ( GHDX) is a molecular diagnostics company focused on the development and global commercialization of genomic-based clinical laboratory services, which analyzes the underlying biology of cancer, allowing physicians and patients to make individualized treatment decisions. This stock is trading up 1% at $28.84 in recent trading after hitting a 52-week of $28.90 earlier in the day.

Today's Range: $28.39-$28.90

52-week Range: $19.00-$28.90

Volume: 32,000 shares

Three-Month Average Volume: 174,591 shares

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Genomic Health, one of TheStreet Ratings' top-rated biotech stocks, has a market cap of $849.04 million and an enterprise value of $764.87 million. The stock trades at a trailing price-to-earnings of 130.64 and a forward price-to-earnings of 70.10. Its estimated growth rate for this year is 92.9%, and for next year it's pegged at 51.9%.

From a technical standpoint, this stock is starting to flirt with a big breakout now that shares are pushing up towards some past overhead resistance at $28.78. Market players should watch for a sustained move and close above $28.78 on high-volume to trigger a bigger trend higher for Genomic Health. So far today, the volume is very light, so watch how the volume looks at the close. If we do get the breakout, then this stock will be trading in all-time high territory, which is bullish.

Staar Surgical

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Staar Surgical ( STAA) designs, develops, manufactures and sells implantable lenses for the eye. STAAR makes lenses both for use in surgery that treats cataracts, and for use in corrective or refractive surgery. This stock is trading up 0.37% at $10.81 in recent trading after hitting a 52-week of $10.88 earlier in the day.

Today's Range: $10.48-$10.88

52-week Range: $4.41-$10.88

Volume: 112,000 shares

Three-Month Average Volume: 356,173 shares

Staar Surgical has a market cap of $390.56 million and an enterprise value of $376.18 million. The stock trades at a trailing price-to-earnings of 983.64 and a forward price-to-earnings of 67.62. Its estimated growth rate for next year is pegged at 166.7%.

From a technical standpoint, this stock recently triggered a breakout trade once it took out some near-term overhead resistance at $10.03 on monster volume. As long as this stock can remain above that key breakout level, then this stock should continue to trend much higher. The next significant overhead resistance levels to watch for a potential target if this breakout holds are $12 to $15.

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Manhattan Associates

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Manhattan Associates ( MANH) develops, sells, deploys, service s and maintains supply chain software solutions. This stock is trading up 1.6% at $46.30 in recent trading after hitting a 52-week of $46.37 earlier in the day.

Today's Range: $45.69-$46.37

52-week Range: $28.11-$46.37

Volume: 33,000 shares

Three-Month Average Volume: 167,933 shares

Manhattan Associates has a market cap of $957.79 million and an enterprise value of $841.48 million. The stock trades at a trailing price-to-earnings of 24.7 and a forward price-to-earnings of 19.45. Its estimated growth rate for this year is 61.6%, and for next year it's pegged at 6.7%.

From a technical standpoint, this stock is starting to break out today above some near-term overhead resistance at $45.30. Market players should now watch for a sustained move and close above $45.30 on high-volume. So far today, the volume is tracking in very light, so watch how it registers at the close. If we do see a decent volume day and a close over $45.30, then this stock should setup to hit $50 a share in the coming days or weeks.

To see more stocks hitting new 52-week highs today, check out the Stocks Hitting New 52-Week Highs portfolio on Stockpickr.

-- Written by Roberto Pedone in Winderemere, Fla.

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At the time of publication, author had no positions in stocks mentioned.

Roberto Pedone, based out of Windermere, Fla., is an independent trader who focuses on stocks, options, futures, commodities and currencies. He is also an outside contributor to Beconequity.com and maintains the website Maddmoney.net, which he sold to Blue Wave Advisors in 2008. Roberto studied International Business at The Milwaukee School of Engineering, and he spent a year overseas studying business in Lubeck, Germany.

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