NEW YORK ( Stockpickr) -- At Stockpickr, we track daily portfolios of stocks that are hitting new 52-week highs and 52-week lows.

It often follows that a stock setting a new 52-week high will continue to set higher and higher highs (and the opposite for a stock setting a new 52-week low), and momentum traders often look to the 52-week-high lists for new stock ideas. Keep in mind, though, that new high prices can also indicate reasons for concern or caution in a stock.

Let's take a closer look at several stocks that hit new 52-week highs today.

>>5 Big Stocks to Trade for Gains

Cubist Pharmaceuticals ( CBST) is focused on the research, development and commercialization of pharmaceutical products that address unmet medical needs in the acute care environment. It was recently trading up $2.57, or 7.1%, at $38.99 after hitting a 52-week high of $39.74 earlier in the day.

Today's Range: $37.55-$39.74

52-Week Range: $20.81-$39.74

Volume: 4.3 million

Cubist has a market cap of $2.2 billion and a short interest ratio of 8.3, and it trades at a P/E of 47.9. Of 15 analysts covering the stock, 11 rate it a buy, and four rate it a hold. TheStreet Ratings' has a B buy rating on Cubist, making it one of the top-rated biotech stocks.

Cubist, which was featured this week in " 5 Stocks Poised to Pop on Earnings," announced third-quarter earnings yesterday that beat analyst estimates and raised its revenue expectations for the full year.

Select Comfort ( SCSS) develops, manufactures, markets and distributes adjustable-firmness beds and other sleep-related accessory products. It was recently trading up $2.65, or 16.4%, at $18.77 after hitting a 52-week high of $19.40 earlier in the day.

Today's Range: $17.64-$19.40

52-Week Range: $6.63-$19.40

Volume: 3.4 million

Select Comfort has a market cap of $902 million and a short interest ratio of 5.8, and it trades with a P/E of 19.7. Of nine analysts covering the stock, six rate it a buy, and three rate it a hold. TheStreet Ratings' has a C+ hold rating on Select Comfort.

On Wednesday, Select Comfort announced a 63% increase in third-quarter earnings and raised its expectations for the full year.

Varian Semiconductor ( VSEA) is a supplier of ion implantation systems used in the fabrication of integrated circuits, which it refers to as microchips or chips. It was recently trading up a penny at $62.75 after hitting a 52-week high of $62.81 earlier in the day.

Today's Range: $62.73-$62.81

52-Week Range: $28.73-$62.81

Volume: 924,000

Varian has a market cap of $4.8 billion and a short ratio of 0.6, and it trades at a P/E of 17. Of 10 analysts covering the stock, two rate it a buy, and eight rate it a hold. TheStreet Ratings' has a B buy rating on Varian Semiconductor, earning the stock a spot on its top-rated semiconductor stocks list.

Varian is one of the holdings of Moore Capital, as of the most recently reported period.

Domino's Pizza ( DPZ), through its subsidiaries, is engaged in retail sales of food through Domino's Pizza stores, sales equipment and supplies to Domino's Pizza stores and receipt of royalties from domestic and international Domino's Pizza franchise. It was recently trading off 43 cents, or 1.4%, at $30.59 after hitting a 52-week high of $31.24 earlier in the day.

Today's Range: $30.39-$31.24

52-Week Range: $13.97-$31.24

Volume: 596,000

Domino's has a market cap of $1.8 billion and a short ratio of 3.9, and it trades at a P/E of 21.1. Of 11 analysts covering the stock, five rate it a buy, and six rate it a hold. TheStreet Ratings' has a B- buy rating on Domino's.

On Tuesday, Domino's reported third-quarter earnings that beat analyst estimates.

PetSmart ( PETM) is a specialty provider of products, services and solutions for the lifetime needs of pets. It was recently trading up 2 cents at $46.73 after hitting a 52-week high of $47.25 earlier in the day.

Today's Range: $46.37-$47.25

52-Week Range: $35.59-$47.25

Volume: 359,000

PetSmart has a market cap of $5.3 billion and a short interest ratio of 3.3, and it trades at a 20.4 P/E. The stock yields 1.2%. Of 18 analysts covering the stock, eight rate it a buy, and 10 rate it a hold. TheStreet Ratings' has an A- buy rating on PetSmart, earning the stock a spot on its top-rated specialty retail stocks list.

PetSmart is also one of the top-yielding specialty retail stocks.

Wisconsin Energy ( WEC), through its subsidiaries, provides utility services such as distributing electric, gas, steam and water. It was recently trading off by a penny at $32.31 after hitting a 52-week high of $32.61 earlier in the day.

Today's Range: $32.29-$32.61

52-Week Range: $27-$32.61

Volume: 413,000

Wisconsin Energy has a market cap of $7.6 billion and a short ratio of 4.2. It trades at a P/E of 14.8 and yields 3.2%. Of 14 analysts covering the stock, six rate it a buy, and eight rate it a hold. TheStreet Ratings' has an A- buy rating on Wisconsin Energy, earning it a spot on the top-rated integrated utilities stocks list.

Pizza Inn Holdings ( PZZI) and its subsidiaries operate and franchise pizza buffet, delivery, carry-out and express restaurants domestically and internationally. It was recently trading up 21 cents, or 5%, at $4.45 after hitting a 52-week high of $4.57 earlier in the day.

Today's Range: $4.25-$4.57

52-Week Range: $1.85-$4.57

Volume: 84,000

Pizza Inn has a market cap of $34 billion and a short ratio of 0.3, and it trades at a P/E of 24.9. TheStreet Ratings' has a B buy rating on the stock.

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