99 Cents Only Stores ( NDN) is engaged in the sale of various consumer products through its retail stores at price points of mainly 99cents or less.. The stock is trading up 12 cents at $21.51 in recent trading.

Volume: 5.3 million

Average Volume: 1.3 million

Volume % Change: 303.9%

99 Cents Only is one of TheStreet Ratings' top-rated multiline retail stocks.

Vertex Pharmaceuticals ( VRTX) is engaged in the business of discovering, developing and commercializing small molecule drugs for the treatment of serious diseases. The stock is trading up $3.47, or 8.6%, at $43.71 in recent trading.

Volume: 6.2 million

Average Volume: 2.4 million

Volume % Change: 161.6%

On Wednesday, IMS Health said it may have misreported data for Vertex's hepatitis C drug Incivek.

Vertex shows up on a recent list of 10 Hep C Stocks on Wall Street's Watch List as well as 11 Biotech Stocks Loved or Hated by Hedge Funds.

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