Dr. Dan Rose, President and Chief Executive Officer of the Pulmonary Fibrosis Foundation, added, “Our Foundation is very excited to be able to fund these important next steps in the therapeutic evaluation of this very promising discovery. We hope that these efforts will lead to a follow-up collaborative development program and ultimately to an effective treatment for this devastating disease.”“Compugen is very enthusiastic regarding this collaboration designed to further evaluate CGEN-25009, an attractive product candidate with potential use not only in fibrosis, a key unmet medical need, but also in other clinical indications, such as labor complications, infertility and heart failure,” said Dr. Anat Cohen-Dayag, Compugen’s president and CEO. “As previously disclosed, Compugen is focusing its discovery and development efforts towards addressing unmet medical needs in the fields of oncology and immunology through the use of novel protein and antibody therapeutics. However, our underlying predictive discovery capabilities are broadly applicable and as part of the development and validation activities associated with establishing these capabilities, a number of very promising discoveries were made in other areas of medical need, both therapeutic and diagnostic. Therefore, although our primary business development efforts are directed towards our oncology and immunology Pipeline Program and 'discovery on demand' activities, we are now in various discussions for arrangements with other organizations to advance certain of these earlier discoveries, including a number of promising novel peptides, largely without the need for further Compugen financial resources, such as the collaboration being announced today.” About Idiopathic Pulmonary Fibrosis Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by scarring of the lung parenchyma leading to severely compromised gas exchange and ultimately to respiratory failure. Despite a significantly improved understanding of the molecular and cellular mechanisms of this disease, the prognosis is still poor, with a median survival of 3 years from the onset of symptoms. There is no known effective treatment, other than, in certain cases, lung transplantation. IPF is estimated to affect more than five million people worldwide.
About the Pulmonary Fibrosis FoundationThe mission of the Pulmonary Fibrosis Foundation (PFF) is to help find a cure for idiopathic pulmonary fibrosis (IPF), advocate for the pulmonary fibrosis community both locally and in Washington, D.C., promote disease awareness, and provide a compassionate environment for patients and their families. Its agenda includes:
- substantially increasing funding for IPF research and assisting in creating partnerships between the academic research community and the biotech industry to drive new treatments;
- fostering collaboration in the clinical community to share information and ideas, starting with the creation of an annual “IPF Summit” beginning in 2011, to improve channels of communication between researchers;
- sponsoring a series of web-based educational seminars (“webinars”) to bring the latest information and research to patients and families more efficiently;
- establishing a National Affiliate Program to allow the PFF to reach new communities, grow its patient outreach capabilities, and expand its fundraising, advocacy, and disease awareness efforts;
- strongly advocating for the IPF community both locally and nationally;
- aggressively pursuing an increase in public awareness through a series of public service announcements, social networking, and traditional media exposure.