Hooper Holmes (NYSE Amex:HH) has been selected as the biological sample collection lead for the largest government study of tobacco use ever conducted in the United States.

The study is a landmark collaboration between the National Institutes of Health and the U.S. Food and Drug Administration. It is the first large-scale project on tobacco regulatory research since Congress granted FDA the authority to regulate tobacco products in the Family Smoking Prevention and Tobacco Control Act of 2009. Scientific experts at NIH's National Institute on Drug Abuse and the FDA's Center for Tobacco Products will coordinate the effort.

The study is properly known as the Tobacco Control Act National Longitudinal Study of Tobacco Users. Westat, in Rockville, MD., was awarded the research contract by the National Institute on Drug Abuse in a competitive solicitation process and has designated Hooper Holmes as the biological sample collection lead.

Over five years, investigators will follow more than 40,000 users of tobacco products nationwide and those at risk for tobacco use ages 12 and older. Participants will be interviewed annually and biological samples will be collected by Hooper Holmes.

“This five year study draws upon several of our strengths, including our national network of local health professionals and Heritage Labs’ kit manufacturing,” said Ransom J. Parker, President and CEO of Hooper Holmes. “Hooper Holmes is uniquely equipped to support longitudinal research studies and we are proud to have been selected as a partner in the Westat consortium.”

Hooper Holmes will collect buccal cell, urine and blood samples from participants and provide collection kits. Buccal cell samples are samples taken by swabbing the cheek inside the mouth. Collection kits will be manufactured at Hooper Holmes’ Heritage Labs division based in Olathe, KS.

Hooper Holmes will select and train phlebotomists from the Company’s national network of 9,000 local health professionals to collect samples following study protocols.

The Company values its participation in the Westat consortium at approximately $6.7 million in revenue over five years, beginning in 2012.

About Westat

Westat is an employee-owned research corporation consulting in statistical design, data collection and management, and research analysis. Westat is one of the foremost research and statistical survey organizations in the United States and provide services to agencies of the U.S. Government, as well as businesses, foundations, and state and local governments.

In addition to its capabilities as a leading statistical survey organization, Westat has extensive skills and experience in custom research, program evaluation studies, and communications campaign development across a broad range of subject areas, as well as technical expertise in survey and analytical methods, computer systems technology, biomedical science, and clinical trials. Westat's staff of more than 2,000 is located at the company’s headquarters in Rockville, MD., near Washington, DC. Westat also maintains research offices in six other U.S. cities and worldwide.

About Hooper Holmes

Hooper Holmes is a leader in collecting personal health data and transforming it into useful information, enabling customers to take actions that manage or reduce their risks and expenses. With presence in hundreds of markets and a network of thousands of examiners, Hooper Holmes can arrange a medical exam anywhere in the U.S. and deliver the results to its customers.

Hooper Holmes has four divisions. Portamedic provides a wide range of medical exam services nationwide. Heritage Labs tests millions of samples annually and helps life insurers improve underwriting performance by better applying the predictive powers of today’s tests. Hooper Holmes Health & Wellness provides a complete service for wellness, disease management, and managed care companies including scheduling support, fulfillment of supplies, blood collection kits, medical screenings, lab testing and data transmission. Hooper Holmes Services reduces the insurance sales cycle through integrated data collection, tele-interviewing and underwriting services.

This press release contains “forward-looking” statements, as such term is defined in the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on the Company’s current expectations and beliefs and are subject to a number of risks, uncertainties and assumptions. Among the important factors that could cause actual results to differ materially from those expressed in, or implied by, these forward-looking statements are our ability to successfully implement our business strategy; uncertainty as to our working capital requirements over the next 12 to 24 months; our ability to maintain compliance with the financial covenant in our credit facility; our expectations regarding our operating cash flows; and the rate of life insurance application activity. Additional information about these and other factors that could affect the Company’s business is set forth in the Company’s annual report on Form 10-K for the year ended December 31, 2010, filed with the Securities and Exchange Commission on March 14, 2011. The Company undertakes no obligation to update or release any revisions to these forward-looking statements to reflect events or circumstances after the date of this press release to reflect the occurrence of unanticipated events, except as required by law.

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