IsoRay, Inc. (Amex: ISR) announced another milestone, today, in the use of its proprietary Cesium-131 (Cs-131) brachytherapy seeds (internal radiation therapy). University of Kentucky Radiation Oncologist Dr. Marcus E. Randall performed the world's first Cesium-131 brachytherapy seed implant for gynecological cancer on a female patient whose cancer had reoccurred following previous radiation treatment. Dr. Randall, voted one of the nation's leading radiation oncologists by US News, performed the surgery at the University of Kentucky's Markey Cancer Center in Lexington, Kentucky where he is the Markey Foundation Endowed Chair of the Department of Radiation Medicine.

Dr. Randall explains , "Cesium-131 is an exciting new isotope that I have begun to use for permanent interstitial implants (brachytherapy or internal radiation therapy). In my gynecologic cancer radiation oncology practice, I often see patients with small recurrences or new primary tumors in the female genital tract in patients who have previously had radiation therapy. Although options have been historically limited to exenterative surgery (surgical removal of organs and tissue) or palliative chemotherapy (a therapy not used to cure, but to prolong life and improve cancer symptoms), I have found that permanent seed implants to these limited volumes are very safe and quite effective with good long term control and survival."

Dr. Randall notes that using Cesium-131 brachytherapy offers many benefits, " Cesium-131 has multiple properties that make it an ideal isotope for these cases. The short half-life gives a good initial dose rate, the low energy enhances radiation safety for the staff, and the dose distribution properties make it easy to calculate and use in the clinic. I have had good initial experiences with this isotope."

Radiation is one of the most important and potent weapons used in treating cancers. IsoRay's patented Cesium-131 brachytherapy seeds represent the biggest advancement in internal radiation therapy in twenty years, providing several advantages over other internal radiation therapies. Cesium-131 allows for the internal radiation treatment of many different cancers because of its unique combination of high energy (its distinctive tissue penetrating capability reaching just far enough to treat the cancer) and its 9.7 day half-life (its matchless speed in giving off therapeutic radiation). Doctors can vigorously treat a variety of cancers with reduced side effects and limited damage to healthy surrounding tissues and organs compared to other internal radiation therapies. This pioneering treatment impacts longevity and cure rates, can be performed outside a hospital setting, and results in a patient's faster return to normal activities. The treatment can be deployed using several delivery methods including single seed applicators, implantable strands and mesh, and several new implantable devices .

IsoRay CEO Dwight Babcock says Cesium-131 is becoming known as the ideal isotope to providing more options for doctors and cancer patients that didn't exist before, "The use of Cesium-131 brachytherapy to treat gynecological cancers presents a vital advance in cancer treatment. As more doctors and patients become aware of the many advantages our isotope offers in patient care, we are seeing a growing number of doctors using Cesium-131 to address cancer sites throughout the body. It is repeatedly proving to be a solution for those difficult cases where other treatments have not proven successful as it continues to demonstrate its effectiveness in controlling cancers and improving survivability."

Cesium-131 is FDA-cleared and has CMS codes for the treatment of prostate , lung, ocular melanoma, brain, colorectal, gynecological, and head and neck cancer and other cancers throughout the body.

About IsoRay, Inc.

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