2. Comfort Keepers
Franchises open: approximately 617 in the U.S. and internationally
Revenue last year: up 6.7% from 2009; three-year sales growth of 32%
Nonmedical care
Comfort Keepers was launched in 1997 by a registered nurse, Kris Clum, and her husband Jerry. She was already working in home care but realized her patients needed help with everyday activities.

In 2009, Comfort Keepers was acquired by Sodexo, a Paris-based provider of food and facilities management.

The all-in investment to establish a Comfort Keepers franchise is between $61,000 and $89,000, according to the website.

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