BOSTON ( TheStreet) -- Welcome to June's Biotech Stock Mailbag Live Chat. The floor is yours.

I'm here for the next 90 minutes or so to answer your biotech investing questions and hopefully spark some interactive debate on the hot biotech topics of the day. This chat only works if you participate, so please keep the questions and comments flowing in the box below.

The American Society of Clinical Oncology (ASCO) annual meeting that just ended raised some controversies and issues surrounding Exelixis ( EXEL), YM BioSciences ( YMI) and Neoprobe ( NEOP), so let's discuss.

If you're interested in FDA drug approval decisions, we can hash out the looming catalysts for Fibrocell Sciences ( FCSC.OB), Transcept Pharmaceuticals ( TSPT), NuPathe ( PATH) or Seattle Genetics ( SGEN).

What's the real story behind Titan Pharmaceuticals' ( TTNP.OB) surprise announcement this morning disclosing an FDA meeting to change the statistical plan for the ongoing phase III study of Probuphine?

Ask me questions about the large-cap biotech stocks: Biogen Idec ( BIIB), Celgene ( CELG), Amgen ( AMGN) and Gilead Sciences ( GILD).

Has anyone figured out why Spectrum Pharmaceuticals ( SPPI) wants to buy back its stock? Why is Allos Therapeutics ( ALTH) trading below $2 a share? Will Cell Therapeutics ( CTIC) ever get a new drug approved? Is there any reason to be optimistic about stem cell stocks like Aastrom Biosciences ( ASTM), Cytori Therapeutics ( CYTX) or Geron ( GERN)?

Let's talk about these stocks today, or any other biotech investing subjects that pique your interest. Please join me live.

--Written by Adam Feuerstein in Boston.

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Adam Feuerstein writes regularly for TheStreet. In keeping with company editorial policy, he doesn't own or short individual stocks, although he owns stock in TheStreet. He also doesn't invest in hedge funds or other private investment partnerships. Feuerstein appreciates your feedback; click here to send him an email.