The investigators screened Staph clinical isolates (laboratory strains) and found 15 hVISA using complex culturing methods. The new BACcel™ assay correctly classified 14 of the 15 as hVISA, and 14 of 14 Staph clinical isolates negative for cryptic resistance.Culturing methods to detect hVISA take 3 days or longer, depending on the methods. The BACcel™ system produced results in 4 hours. The test can be used directly from patient specimens, which would add no more than 1 hour to the total processing time. According to David Howson, Accelr8’s president, “the specimen study used types of specimen that may be the most difficult specimens for a lab to analyze. They are highly variable, and contain large amounts of sticky and bulky interfering materials. In the past, new diagnostic tests that have worked well with cultured strains often failed when challenged directly with respiratory specimens. We believe this study demonstrates that we’ve overcome this major hurdle. The study also set a new speed record for counting, identifying, and analyzing multiple targets with multiple resistance tests—only four hours after starting with a specimen. If we consider these results and the results presented a week ago at ATS, the combined data show that the BACcel™ rapid diagnostic system is accurate and very fast.” “The hVISA study also follows a presentation three weeks ago at the European ECCMID meeting that used the BACcel™ hVISA test, along with others. The new results add details that more fully characterize the test performance with this difficult new strain. The ASM study demonstrates the BACcel™ system’s potential for revealing fundamental modes of resistance expression that were neither predicted nor detected using standard culturing methods,” Howson continued. “These and other tests for multiple organisms and multiple resistance expression modes provide the platform for expanded studies and integration into the next BACcel™ generation. We are now widening our key opinion leader network to prepare for these important studies,” Howson concluded.
Downloadable copies of presentations are available on the publications page of Accelr8’s Web site at www.accelr8.com/pgen.php?pg=resources_publications.About Accelr8 Accelr8 Technology Corporation ( www.accelr8.com) is a developer of innovative materials and instrumentation for advanced applications in medical instrumentation, basic research, drug discovery, and bio-detection. Accelr8 is developing a rapid analytical platform for infectious pathogens, the BACcel™ system, based on its innovative surface coatings, assay processing, and detection technologies. In addition, Accelr8 licenses certain of its proprietary technology for use in applications outside of Accelr8’s own products. Certain statements in this news release may be “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Statements regarding future prospects and developments are based upon current expectations and involve certain risks and uncertainties that could cause actual results and developments to differ materially from the forward-looking statement, including those detailed in the company's filings with the Securities and Exchange Commission. Accelr8 does not undertake an obligation to publicly update or revise any forward-looking statements, whether as a result of new information or future events.