A resident drives slowly on River Road north of Yazoo City, Miss., as the flood waters begin to submerge the street on Thursday.

Farmers throughout the southern region watch helplessly as thousands of acres of corn, wheat, soybean and cotton crops along the Mississippi River are submerged in floodwaters.

The rising Mississippi River is also threatening the catfish farmers in the region, many of which are located in the south Mississippi Delta. The state of Mississippi is currently the leading U.S. producer of farm-raised catfish, followed by Alabama and Arkansas.

As the regions continues to flood, farmers race to construct barriers around their ponds, the AP reported.

"If these ponds get flooded, the fish will just become part of the flood," said Taylor Webb, a spokesman for Catfish Farmers of America, a nonprofit trade organization. "Once the water subsides, there are going to be a lot what you call junk fish in there. You have to drain the pond, get everything out and start over."

Harry Simmons, the owner of Simmons Farmed Raised Catfish near Yazoo City, estimates that it will cost $150,000 to wrap a protective levee around his home, business and about 400 acres of catfish ponds.

"We'll just have to see what's there when the water goes down," he said.

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