Epocrates, Inc. (NASDAQ:EPOC), a leading provider of mobile drug reference tools to healthcare professionals and interactive services to the healthcare industry, will release its 2010 fourth quarter and full-year financial results and its financial guidance for 2011 on Tuesday, March 29, 2011, before regular market trading hours.

Epocrates will host a conference call and webcast the same day at 8:30 a.m. Eastern Time. Epocrates’ management will review its 2010 fourth quarter results and full-year operating results and future outlook, followed by a question and answer session.

To participate in Epocrates’ live conference call and webcast, please dial 877-398-9481 (if dialing from within the U.S.) or 760-298-5095 (if dialing from outside the U.S.) using conference code 47269531 or visit the Investor Relations section of Epocrates’ website at http://www.epocrates.com.

A replay of the conference call will be available approximately two hours after the completion of the conference call by dialing 800-642-1687 (if dialing from within the U.S.) or 706-645-9291 (if dialing from outside the U.S.) using conference code 47269531. The replay will be available for one week on the above number. A webcast replay will also be archived on Epocrates’ website for approximately 12 months.

About Epocrates, Inc.

Epocrates is a leading provider of mobile drug reference tools to healthcare professionals and interactive services to the healthcare industry. Epocrates’ active user network currently has more than one million healthcare professionals, including more than 45 percent of U.S. physicians. Most commonly used on mobile devices at the point of care, the company’s clinical products and services help healthcare professionals make more informed prescribing decisions, enhance patient safety and improve practice productivity. For more information about Epocrates, please visit www.epocrates.com/company.

Epocrates is a trademark of Epocrates, Inc., registered in the U.S. and other countries.

Copyright Business Wire 2010

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