NEW YORK ( TheStreet) -- Shares of Genzyme ( GENZ) jumped in after-hours action following a report that the company is once again talking to Sanofi Aventis ( SNY) about a potential merger. Citing people familiar with the situation, the Wall Street Journal said the companies are back at the bargaining table, negotiating terms on a transaction that could value Genzyme shares as high as $80 each. Genzyme's stock was last quoted at $74.25, up 4.1%, on volume of around 380,000, according to Nasdaq.com. The shares finished the regular session at $71.39, down 17 cents, and gained almost 40% in 2010. The Journal report said the $80 per share price being bandied about would be contingent upon Genzyme hitting certain performance milestones. Sanofi's previous bid for Genzyme topped out at $69 per share, which Genzyme's board rejected as too low back in October.