First Interstate BancSystem, Inc. (NASDAQ: FIBK), parent company of First Interstate Bank, will report fourth quarter financial results after the market closes on February 3, 2011. A conference call for investors is scheduled for Friday, February 4, 2011 at 11:00a.m. Eastern Time (9:00a.m. MT), during which the Company will discuss fourth quarter 2010 results. There will be a question and answer session following the presentation.

The conference call will be accessible by telephone and through the Internet. Shareholders, analysts and other interested parties are invited to join the call by dialing 1-877-317-6789. To participate via the Internet, log on to www.fibk.com. A rebroadcast will be available approximately one hour after the end of the conference call by dialing 1-877-344-7529. The conference ID is 447070. The call will also be archived on our Web site, www.fibk.com.

First Interstate BancSystem, Inc. is a financial services holding company, headquartered in Billings, Montana, with $7.3 billion in assets as of September 30, 2010. It is the parent company of First Interstate Bank, a community bank operating 72 offices throughout Montana, Wyoming and western South Dakota. As a recognized leader in community banking services with 22 consecutive years of profitability, First Interstate remains a family business whose culture is driven by strong family and corporate values, as well as a commitment to long-term organic growth, exemplary customer service, exceeding customer expectations through its products and services and supporting, with leadership and resources, the communities it serves.

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