5. Curis ( CRIS) researches and develops cancer therapeutics. Collaborator Genentech just initiated a Phase II trial of GDC-0449. Curis's second-quarter loss decreased 50% to $2.1 million, or 3 cents a share, as revenue expanded 57%. Curis has $45 million of cash and no debt. Its stock trades at a book value multiple of 2.1 and a sales multiple of 7.1, 61% and 93% discounts to industry averages. All five analysts covering Curis recommend that clients purchase its shares. A median price target of $3.75 suggests that the stock will rally 164%. Bullish Scenario: RBC ( RY) forecasts that Curis's stock will appreciate 182% to $4.