NEW YORK ( TheStreet) -- Several stocks trading near $5 were poised to move on above-average volume during Wednesday's session.

MDRNA ( MRNA) opened higher by 84 cents, or 88.6%, to $1.79 after the company reported potent anti-tumor activity against both liver and bladder cancers via both systemic and local delivery with its proprietary UsiRNAs delivered by its novel DiLA2 platform. The 50-day average daily volume for MDRNA is 292,000, according to the Nasdaq.

Hythiam ( HYTM) jumped by 3 cents, or 6.6%, to 54 cents at the start of trading after a published paper sponsored by the company noted predictive models that can be utilized as the basis for Hythiam to develop new and innovative approaches for substance dependence solutions that result in improved member care and reduced costs for payors. The 50-day average daily volume for Hythiam is 1.02 million.

LeCroy ( LCRY) rallied by 47 cents, or 13%, to $4.08 in early trading after the company said it expects fiscal second quarter revenue of approximately $31 million, which is above the $29.9 million average of two analyst estiamtes. The 50-day average daily volume for LeCroy is 25,000.

Affymetrix ( AFFX) slumped by 74 cents, or 11.5%, to $5.70 in early trading after Barclays downgraded the stock to underweight from equal weight. The firm also lowered its price target on Affymetrix to $3 from $6. The 50-day average daily volume for Affymetrix is 1.24 million.

( Earlier at 7:37 a.m. EST.)

OceanFreight ( OCNF) rose by 4 cents, or 4%, to $1.04 in the premarket session after the company late Tuesday filed a $400 million mixed securities shelf offering. The 50-day average daily volume for OceanFreight is 5 million, according to the Nasdaq.

AgFeed Industries ( FEED) announced plans Wednesday for an internal reorganization. AgFeed said it will remain the holding company for two separate, wholly-owned businesses, one for its animal nutrients feed operations and one for its genetic hog production operations. Each business line will have a board of directors, an executive-level management team with strong industry experience, financial systems designed specifically for their operations and internal financing capabilities. The 50-day average daily volume for AgFeed is 1.69 million. The stock finished Tuesday's session at $5.08.

BioCryst Pharmaceuticals ( BCRX) jumped by 47 cents, or 5.9%, to $8.45 in the premarket session after the company said its partner Shionogi receives marketing and manufacturing approval for intravenous peramivir to treat patients with influenza in Japan. BioCryst will receive a third and final regulatory milestone payment of $7 million under its license agreement with Shionogi. BioCryst may receive future commercial event milestone payments of up to $95 million from Shionogi. The 50-day average daily volume for BioCryst is 2.18 million shares.

Flanders ( FLDR) said late Tuesday it will voluntarily delist and deregister its common stock. The firm cited substantial savings it expects to realize from reductions in legal, accounting and other costs. The 50-day average daily volume for is 46,000.

-- Written by Robert Holmes in Boston.

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