NEW YORK (TheStreet) -- CHANGE IN RATINGS

Affymetrix ( AFFX) downgraded at Barclays to Underweight from Equal Weight on major structural challenges. Price target cut in half to $3. 2009 and 2010 EPS estimates set at -$0.47 and -$0.21, respectively.

Brookdale Senior Living ( BKD - Get Report) upgraded at Barclays to Equal Weight from Underweight as their improved liquidity position will provide opportunities for expansion in 2010. Price target jumped to $22 from $18.

Health Management ( HMA) upgraded at Stifel from Hold to Buy. $9.50 price target. Sales turnaround will likely offset rising bad debt expenses.

HJ Heinz ( HNZ) rated new Overweight at Morgan Stanley. $48 price target. Company should outperform in a challenging environment during 2010.

IAC/InterActiveCorp ( IACI) upgraded at Goldman to Buy. $28 price target. Estimates also raised, given momentum in the Search and ServiceMagic units.

Joy Global ( JOYG) upgraded at UBS from Neutral to Buy. $70 price target. Higher commodity prices should lead to an increase in mining CapEx spending.

Kennametal ( KMT) downgraded at Keybanc from Buy to Hold. Shares could be priced to perfection.

Massey Energy ( MEE) upgraded at BofA/Merrill to Buy from Neutral to reflect leverage to higher met coal prices. Price target increased to $57 from $41. 2010 and 2011 EPS estimates raised to $2.30 and $4.40, respectively.

Merck ( MRK - Get Report) upgraded at Credit Suisse to Outperform from Neutral. We expect new interest to come from the pipeline, analyst said. Price target boosted to $47 from $35. 2009 and 2010 EPS estimates set at $3.27 and $3.60, respectively.

NetApp ( NTAP) upgraded at MKM from Neutral to Buy. $41 price target. Strong channel feedback suggests that the company could exceed expectations this quarter.

Spectra Energy ( SE) upgraded at Wells from Market Perform to Outperform. Company could raise guidance at its upcoming analyst meeting, and has a solid pipeline franchise.

Solutia ( SOA) upgraded at Keybanc from Hold to Buy. $18 price target. Company is seeing favorable demand improvement.

Symantec ( SYMC) upgraded at Wells from Market Perform to Outperform. Have a positive outlook for the overall spending environment and the company's new product cycle.

UPS ( UPS) upgraded at RBC from Sector Perform to Outperform. $72 price target. Company is seeing strong demand across the globe and also benefiting from cost-cutting.

STOCK COMMENTS / EPS CHANGES

Aetna ( AET) target, estimates lower at BofA/Merrill. AET price target sunk to $33 from $31 on weaker than expected guidance. 2010 and 2011 EPS estimate lowered to $2.70 and $3.20, respectively. Maintain Underperform rating.

Aetna ( AET) estimates, target reduced at Goldman. Shares of AET now seen reaching $34. Estimates also cut, to match the company's new guidance. Neutral rating.

Charles River ( CRL - Get Report) numbers lowered at Goldman through 2012. Demand recovery is not in sight. Neutral rating and new $32 price target.

Citrix Systems ( CTXS) numbers boosted at Goldman. Shares of CTXS now seen reaching $48. Estimates also raised, to reflect exposure to the PC and server refresh cycles. Buy rating.

Covance ( CVD) estimates, target cut at Goldman. Shares of CVD now seen reaching $50. Estimates also lowered, to reflect continued pricing pressure in the industry. Neutral rating.

Dover ( DOV) price target boosted at BofA/Merrill to $54 from $45 as business fundamentals could exceed expectations near term. 2010 and 2011 EPS estimates raised to $2.50 and $3.15, respectively. Buy rating.

Linear Technology ( LLTC) numbers raised at FBR. Shares now seen reaching $31. Estimates also boosted, as the company is seeing a recovery in industrial demand. Underperform rating.

QLogic ( QLGC) estimates, target raised at Goldman. Shares of QLGC now seen reaching $21.50. Estimates also boosted, to match the company's new guidance. Neutral rating.

Supervalu ( SVU) estimates increased at UBS through 2011. Company has a good quarter on lower promotional spending, but sales trends are troubling. Neutral rating and $13 price target.

Trina Solar ( TSL) target, estimates boosted at BofA/Merrill. Bank of America/Merrill Lynch increased TSL price target to $65 from $55 on higher shipments. 2009 and 2010 EPS estimates raised to $3.30 and $4.42, respectively. Buy rating.

This article was written by a staff member of TheStreet.com.