After the market close, Stockpickr updates a series of portfolios called Today's Lists with information from that trading day. It's a useful tool for getting a quick picture of how the market moved that day.If you are a Stockpickr member and have a Today's List stock in one of your portfolios, you'll receive an email alert after that list is updated. You can become a Stockpickr member here. Here's a sampling of what made Today's Lists today, July 21: 52-Week Highs: Hitting a 52-week high again on Tuesday was Human Genome Sciences ( HGSI), which rose to $14.97 before closing up 10.6% for the day at $13.84. Schering-Plough ( SGP) hit a high of $26.60 and closed up 3.8% for the day at $26.53. Biggest % Gainers: Yingli Green Energy ( YGE) rose 13.9%, or $1.58, on Tuesday, to close at $12.98 on news of Chinese solar subsidies. JDA Software ( JDAS) added $5.65, or 34.4%, to $22.09 on second-quarter earnings. Biggest % Losers: CIT ( CIT) closed down 21.6% at 98 cents on Tuesday. Analyst Upgrades: BMO Capital upgraded Las Vegas Sands ( LVS) to outperform from market perform with a $15 price target. ThinkEquity upgraded NetApp ( NTAP) to accumulate from source of funds with a $22 price target. Analyst Downgrades: Jefferies downgraded Nokia ( NOK) to hold from buy, and Morgan Stanley bumped it down to underweight from overweight. See all of Today's Lists here, including TSC Ratings Upgrades, Unusual Options Activity and TheStreet.com TV Videos.