TSC Ratings provides exclusive stock, ETF and mutual fund recommendations using proprietary tools. Our "safety-first" approach aims to reduce risk while achieving performance on a total return basis.The following large-cap companies have market values of more than $10 billion and receive "buy" ratings from our proprietary quantitative model, which considers more than 60 factors. The stocks are ordered by their potential to appreciate. McDonald's ( MCD) franchises and operates hamburger restaurants worldwide. The numbers: First-quarter revenue declined 10% to $5.07 billion but net income increased marginally to $980 million and earnings per share jumped 7% to 87 cents. Net margin remained strong at 20%. A 32% decline in the cash balance to $1.98 billion is a weakness. But a quick ratio of 1.3 and a debt-to-equity ratio of 0.8 indicate a conservative financial position. The stock: McDonald's has declined 8% in 2009, underperforming the Dow Jones Industrial Average and the S&P 500. The stock trades at a price-to-earnings ratio of 15 and offers a dividend yield of 3.5%. Colgate-Palmolive ( CL) makes and markets consumer products worldwide. The numbers: First-quarter revenue decreased 6% to $3.5 billion but net income climbed 9% to $508 million as earnings per share jumped 13% to 97 cents. The company has established a five-quarter streak of earnings growth despite recessionary pressures. Gross margin increased and is high at 60%. Net operating cash flow ascended 21% as the cash balance improved 9% to $702 million. The stock: Colgate-Palmolive has climbed 6% in 2009, outperforming the Dow and the S&P 500. The stock trades at a price-to-earnings ratio of 20 and offers a 2.4% dividend yield. Medco Health Solutions ( MHS) is one of the nation's largest pharmacy-benefit managers, providing sophisticated traditional and specialty benefit programs. The numbers: First-quarter revenue rose 14% to $14.8 billion, beating the industry average growth rate of 1.1%. Net income increased 8% to $291 million and earnings per share improved 16% to 58 cents. Net operating cash flow increased 607%. The company has added $1.3 billion to the cash balance since the prior year's first quarter. The stock: Medco has ascended 13% in 2009, outperforming the Dow and the S&P 500. The stock is trading at a price-to-earnings ratio of 21 and doesn't pay dividends.