CA ( CA) downgraded at RBC to sector perform from outperform and price target reduced to $20 from $24. Over the next several quarters, RBC believes that investors will shift to more growth names over defensive software stocks, which will likely limit CA's multiple expansion. Covance ( CVD)downgraded at Goldman Sachs to Neutral from Buy due to ongoing weakness in preclinical industry demand. See company as well-positioned long-term but also believe current consensus estimates are too high. Price target trimmed to $40 from $43. Energy Conversion Devices ( ENER) numbers cut at Barclays to $10. Estimates also lowered, to reflect the company's new guidance, based on weak demand. Underweight rating. Energy Conversion Devices ( ENER) downgraded at Jefferies. Rating lowered to Hold from Buy. Price target lowered to $15 from $37. 2009 EPS estimates lowered to $0.80 from $1.32. Ensco ( ESV) upgraded at Deutsche from Sell to Hold. $32 price target. Stock is now pricing in over-supply and weaker shallow-water demand. Estimates also raised, to reflect new Mexico jackup contracts. Goldman Sachs ( GS) downgraded at Keefe, Bruyette & Woods from Outperform to Market Perform. Don't see catalysts for further multiple expansion. $101 price target. Home Depot ( HD) upgraded at Jefferies to Buy from Hold based on strong capital discipline and accelerating market share gains. Raises target price to $24 from $20. JP Morgan ( JPM) upgraded at Merrill/BofA to Buy. $40 price target. Stock still looks cheap based on book value, which is discounting mid-single digit ROE.