Indevus ( IDEV) shares slid 69% to $1.26 Wednesday on news of a Food and Drug Administration delay. The company said regulators will not approve Nebido, a long-acting injectable testosterone, without additional safety data and a new clinical trial expected to take 18 months.

AMD ( AMD) gained 39 cents, or 5.7%, to $7.20 after the company unveiled a new group of chips, named Puma, specifically designed for notebooks. The move represents AMD's most concerted effort to enter the growing market for mobile PCs.

Tibco ( TIBX) shed 60 cents, or 7.8%, to $7.12 after the company said second-quarter profit would fall short of expectations.

The company said EPS, excluding special items, would be 5 cents or 6 cents, vs. analysts' estimates for 8 cents. Revenue during the quarter is likely to range between $147 million and $149 million. Analysts were expecting a top line of $154.1 million.

Diagnostics company Sequenom ( SQNM), surged 21.8% to $9.33 after announcing that its SEQureDX, a prenatal screening test for maternal blood for Down Syndrome, was effective in all samples (200 were tested) without any false positives. The results were superior to current serum-testing options, which have detection rates between 70% to 90% and false-positive rates as high as 5%.

Sequenom plans to initiate a multisite validation study, which will include several thousand samples, in the fourth quarter this year and to launch the test in the U.S. in the first half 2009. The company said it plans to transfer the technology to its laboratory partners at the end of this year.

Bob Evans Farms ( BOBE) climbed 15.5% to $33.60 after the restaurant chain posted better-than-expected fourth-quarter earnings after Tuesday's market close. The company earned $16.1 million, or 52 cents a share, compared with $15.3 million, or 42 cents a share, a year ago. Sales came to $436.4 million, up from $418.4 million last year. Analysts were looking for earnings of 41 cents a share on $441.5 million in revenue, according to Thomson Reuters data. Looking forward, Bob Evans expects fiscal 2009 earnings of $2 to $2.10 a share.

Frontier Financial ( FTBK), the Everett, Wash.-based holding company for Frontier Bank said it was ending its merger with Washington Banking ( WBCO). Frontier lost 3.9% to $13.97, and Washington Banking plummeted 20% to $10.01.

This article was written by a staff member of TheStreet.com.

More from Investing

Starbucks Stock Is Still Plunging

Starbucks Stock Is Still Plunging

Online Retailers Hit by Supreme Court Ruling Requiring Sales Tax Collection

Online Retailers Hit by Supreme Court Ruling Requiring Sales Tax Collection

Tesla Received Tip That Former Employee Was Going to 'Shoot the Place Up'

Tesla Received Tip That Former Employee Was Going to 'Shoot the Place Up'

Jim Cramer: Williams Sonoma Is a Digitized Play

Jim Cramer: Williams Sonoma Is a Digitized Play

This Is What's Hot Thursday - Stocks Slide, Intel's CEO Woes & Major Movers

This Is What's Hot Thursday - Stocks Slide, Intel's CEO Woes & Major Movers