On Friday sullen health indices proved immune to a compelling deluge of post-close earnings the day prior and yet another job slashing.

King Pharmaceuticals ( KG) said Thursday after close that it's cutting its workforce by 20% in light of challenges to its Altace franchise and to refocus on neuroscience and hospital/acute care.

In September, the U.S. Court of Appeals ruled against the continued validity of the patent covering blood-pressure drug Altace. (King filed a petition with the court seeking reconsideration of the decision.)

King will incur special charges in 2007 of about $150 million to recognize the impaired value of its intangible assets associated with Altace and about $90 million primarily related to the impaired value of raw material inventory and related contracts associated with Altace. The company estimated that it will also incur a one-time charge of around $70 million during 2007 related to the restructuring, and predicts 2008 savings between $75 million and $90 million from the cut.

Shares edged up 13 cents, or 1.2%, at $10.85. The stock is a component of the Amex pharmaceutical index, which was down 92 cents, or 0.3%, to $347.33.

Intuitive Surgical ( ISRG) reported Thursday after close that quarterly net income rose to $40.9 million, or $1.04 a share, from $17.3 million, or 45 cents a share, in the prior-year quarter. Revenue rose 64% to $156.9 million from $95.8 million in the third quarter of 2006. Revenue was boosted by a 63% increase in sales of the company's da Vinci Surgical System.

Analysts surveyed by Thomson Financial expected 80 cents a share on revenue of $143.5 million. On Friday HSBC Securities upped its price target for the company to $325 from $198. Shares climbed $22.06, or 8.6%, to $278.50.

Also up was Ventana Medical ( VMSI), which late Thursday reported earning $263,000, or a penny a share, compared with $7.8 million, or 22 cents a share, in the year-ago quarter. Excluding special charges and one-time items, the company reported earning $7.9 million, or 22 cents a share. The Thomson Financial consensus target was 19 cents a share on revenue of $73 million.

The company raised its expectations for 2007 adjusted income to around $1.34 a share, compared to its previous prediction of $1.31 a share, and now expects revenue in the range of $296 million to $300 million, up from a previously discussed range of $292 million to $296 million. Shares rose 99 cents, or 1.1%, to $89.30.

In another postclose earnings release Thursday, Gilead ( GILD) reported net income of $398.3 million, or 42 cents a diluted share, including after-tax stock-based compensation expenses of $31.8 million, compared to a loss of 3 cents in the year-ago quarter. The consensus was 39 cents a share on revenue of $1 billion.

Gilead also named Caroline Dorsa senior vice president and chief financial officer, effective in November to replace John Milligan appointed chief operating officer in March.

Rodman & Renshaw upped its price target for the stock to $56 from $43, but the stock fell $1.32, or 3%, to $42.41 on Friday.

And on Friday morning, Boston Scientific ( BSX) reported a loss of $272 million, or 18 cents a share, compared to a profit of $76 million, or 5 cents a share, in the year-ago quarter.

But factoring out after-tax acquisition- and divestiture-related charges of $435 million, or 29 cents a share, the company said it earned adjusted income of $299 million, or 20 cents a share, compared to $271 million, or 18 cents a share, on the same basis in the year-ago quarter.

Analysts surveyed by Thomson Financial expected 7 cents a share, on revenue of $2.057 billion. Boston Scientific shares climbed 90 cents, or 6.8%, to $14.74.

In conjunction with Boston Scientific's earnings release, Angiotech Pharmaceuticals ( ANPI) gave preliminary results and lowered forecasts.

The company, which makes the paclitaxel coating for the Boston Scientific's drug-eluting stents which prop open clogged arteries, cut its 2007 royalty revenue outlook to a range of $118 million to $120 million compared to prior guidance of $130 million to $135 million. It also lowered its medical product revenue outlook to a range of $171 million to $173 million from $190 million to $210 million.

Angiotech predicted adjusted earnings before interest, taxes, depreciation and amortization of $47 million to $50 million for the year, compared to the prior expectation of $85 million to $95 million. Shares gave up $2.58, or 34.3%, to $4.95.

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