Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity. 52-Week Highs: The Chicago Board of Trade soared 7% as the Chicago Mercantile Exchange ( CME - Get Report) once again raised its offer for the exchange in an effort to outdo a competing takeover proposal from InterContinental Exchange ( ICE - Get Report). Chicago Board of Trade shares climbed $17.85 to a 52-week high of $224. Biggest % Gainers: Applied Mirco Circuits ( AMCC) climbed over 14% Friday, as the company cut first-quarter sales outlook, but also forecasted growth in the second quarter and promised to cut its operating expenses. The chipmaker was up 36 cents to $2.80. Biggest % Losers: Mannatech ( MTEX) fell 22% Friday on word that the Texas attorney general is suing the dietary supplement maker for deceptive trade practices. "We are aware of the situation and will be taking appropriate action to address any issues or concerns from the Texas Attorney General's office," Mannatech said. Its stock closed down $3.75 to $12.25. 52-Week Lows: Interactive Brokers Group ( IBKR - Get Report) on Friday dropped to a 52-week low of $24.97 after the company predicted a smaller second-quarter profit due to a loss in the sale of certain claims. The Greenwich, Conn.-based company was down 8% or $2.14. Rising on Unusual Volume: Grupo Areoportuario Del Paci ( PAC - Get Report) was up 2% amid 330% increase in daily trading volume. The company engages in the management, operation, and development of airport facilities in Maxico's Pacific Region. Shares closed up $1.05 to $51.85. Stocks with Unusual Option Activity: Pain Therapeutics ( PTIE) was experiencing unusual options activity Friday, but shares remained unchanged. Latest Activist Situations: Nelson Peltz's Trian Fund Management disclosed a 9.8% stake in Wendy's ( WEN - Get Report). Peltz has acknowledged he is considering buying Wendy's. The stock closed down 24 cents, or 0.6%, to $38.