Editor's Note: In this feature from Stockpickr, we highlight lists of stocks that have made new highs, lows or seen other unusual activity.

52-Week Highs: Bausch & Lomb ( BOL) shares rose 9.8% to $67.50, a 52-week high, on news it agreed to be acquired by private-equity firm Warburg Pincus.

Biggest % Gainers: Monolithic Power Systems ( MPWR) jumped 16% to $16.62, the day's biggest percentage gain. The semiconductor company benefited from a favorable verdict from a California jury in a patent infringement lawsuit.

The company also was Rising on Unusual Volume. Shares were trading at more than nine times average.

Biggest % Losers: Arrhythmia Research Technology ( HRT) sank 35%, flat-lining with the day's biggest percentage drop. The company announced disappointing earnings Wednesday.

52-Week Lows: Gaming Partners International ( GPIC) plummeted 32% to $10.83, a 52-week low. The gaming-chip manufacturer posted disappointing earnings.

Latest Activist Situations: Shamrock Activist Value Fund disclosed late on Tuesday that it had upped its stake to 6.37% in Modine Manufacturing ( MOD), which makes engine cooling components.

Forum of the day

Syntax-Brillian ( BRLC): Sell or back up the truck? HazyDavy asks.

Do you know the answer?

Does Wachovia's downgrade of Bear Stearns ( BSC) raise concerns for other banks, such as Goldman Sachs ( GS)? windwardskies asks.

Feeling lucky?

And finally, try picking a random portfolio suited to do-it-yourselfers with more detailed analysis at I'm Feeling Lucky.

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